Peptide Database

Anti-Obesity Drug 9604 · hGH Fragment 177-191

AOD-9604 is a modified fragment of human growth hormone (hGH 177-191) that retains the lipolytic properties of GH without its anabolic or diabetogenic effects. It stimulates lipolysis through β3-adrenergic receptor pathways and inhibits lipogenesis. Phase 3 trials for obesity were conducted; it has since been investigated for osteoarthritis through cartilage repair properties.

Body Protection Compound 157 · PL 14736

BPC-157 is a 15-amino-acid peptide fragment derived from human gastric juice. It is one of the most extensively researched peptides for tissue repair, demonstrating accelerated healing of tendons, ligaments, muscle, bone, and gut lining in animal models. It appears to upregulate growth hormone receptors and promote angiogenesis at injury sites.

C₆₂H₉₈N₁₆O₂₂ · 1419.55 Da

CJC-1295 with DAC · DAC:GRF

CJC-1295 is a modified GHRH analog with a Drug Affinity Complex (DAC) that binds to serum albumin, dramatically extending its half-life compared to native GHRH. It produces sustained elevation of GH and IGF-1 levels over days rather than hours. Research focuses on body composition improvements, muscle growth, and fat loss through prolonged GH axis stimulation.

C₁₅₂H₂₅₂N₄₂O₄₂S · 3647.28 Da

Delta Sleep Inducing Peptide · Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

DSIP (Delta Sleep Inducing Peptide) is a nonapeptide first isolated from rabbit cerebral venous blood during electrically induced sleep. Research shows it promotes slow-wave sleep, reduces pain sensitivity, normalizes circadian rhythms, lowers cortisol, and exhibits stress-protective effects. It also stimulates LH release and may influence GH pulsatility. Multiple mechanisms of action are proposed; its receptor has not been fully characterized.

Epitalon · Epithalamin

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on the endogenous pineal peptide epithalamin. It is one of the most extensively studied longevity peptides, with Russian research demonstrating telomerase activation, telomere elongation, melatonin normalization, and extended lifespan in animal models. Long-term human studies show reduced all-cause mortality rates and improved biomarkers of aging.

HGH Frag 176-191 · Growth Hormone Fragment 176-191

Fragment 176-191 is the C-terminal amino acid sequence 176–191 of human growth hormone, closely related to AOD-9604. It mimics the lipolytic activity of natural GH without binding to the GH receptor, thus avoiding insulin resistance and proliferative effects. Research shows it reduces fat mass in animal models by enhancing fat metabolism and inhibiting new fat formation.

Copper Peptide GHK · Glycyl-L-histidyl-L-lysine copper

GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. Research demonstrates it stimulates collagen, elastin, and glycosaminoglycan synthesis, promotes wound healing, reduces inflammation, and activates protective antioxidant genes. Plasma levels decline with age, making it a significant anti-aging research target.

C₁₄H₂₄CuN₆O₄ · 340.84 Da (free ligand)

Examorelin · EP 23905

Hexarelin is one of the most potent synthetic GHRP compounds, producing the largest GH pulse among GHRPs. Beyond its GH-stimulating properties, research highlights direct cardioprotective effects through CD36 receptor binding, independent of GH or IGF-1. Studies show benefits in heart failure models, myocardial infarction recovery, and protection against ventricular dysfunction.

NNC 26-0161

Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. Unlike other GHRPs, it stimulates GH release with high selectivity — producing minimal cortisol, ACTH, or prolactin elevation. It is among the most studied GHRPs for its clean GH pulse profile, making it a preferred research peptide for GH axis studies with reduced side effect concern.

C₃₈H₄₉N₉O₅ · 711.86 Da

Bremelanotide · Vyleesi

PT-141 (bremelanotide) is a cyclic heptapeptide melanocortin receptor agonist, FDA-approved for hypoactive sexual desire disorder (HSDD) in premenopausal women. Unlike PDE5 inhibitors, it acts centrally through MC3R and MC4R receptors in the hypothalamus to initiate sexual arousal, making it effective for psychological as well as physiological sexual dysfunction. Research also explores applications in male erectile dysfunction.

Selanc · TP-7

Selank is a synthetic heptapeptide analog of tuftsin developed by the Russian Institute of Molecular Genetics. Approved in Russia for anxiety and cognitive disorders, it exhibits anxiolytic effects comparable to benzodiazepines without sedation or dependence. Research shows it modulates GABA, serotonin, and dopamine systems, enhances BDNF expression, and improves memory consolidation and learning.

C₃₃H₅₇N₁₁O₉ · 751.87 Da

Ozempic · Wegovy

Semaglutide is a long-acting GLP-1 receptor agonist approved for type 2 diabetes (Ozempic, Rybelsus) and obesity (Wegovy). By mimicking the incretin hormone GLP-1, it enhances glucose-dependent insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite via central hypothalamic pathways. Landmark trials demonstrate up to 15–17% body weight reduction and significant cardiovascular mortality benefit.

MEHFPGP · Pro8-Gly9-Pro10-ACTH(4–10)

Semax is a synthetic heptapeptide analog of ACTH(4-7) developed in Russia, where it is approved for stroke, TBI, peptic ulcers, and cognitive enhancement. It upregulates BDNF and its receptor TrkB, promotes dopamine and serotonin turnover, and has demonstrated neuroprotective effects in ischemia models. Research highlights improvements in attention, memory, and recovery from neurological injury.

GHRH(1-29) · GRF 1-29 NH2

Sermorelin is a synthetic analog of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). It stimulates the pituitary to produce and secrete growth hormone in a pulsatile, physiologic manner. FDA-approved for GH deficiency in children, it is extensively researched in adults for body composition, sleep quality, and age-related GH decline.

C₁₄₉H₂₄₆N₄₄O₄₂S · 3357.88 Da

Thymosin Beta-4 Fragment · Tβ4 fragment

TB-500 is a synthetic version of the active region of Thymosin Beta-4, a naturally occurring peptide found in virtually all human cells. Research shows it promotes actin polymerization and cell migration, which accelerates wound healing, muscle repair, and vascular growth. It is particularly studied for its ability to reduce inflammation and promote cardiac tissue repair.

C₂₁₂H₃₅₀N₅₆O₇₈S · 4963.44 Da

Egrifta · TH9507

Tesamorelin is a stabilized synthetic GHRH analog FDA-approved for reduction of excess abdominal fat in HIV-infected adults with lipodystrophy. It stimulates pulsatile GH secretion while preserving natural feedback regulation. Research demonstrates significant visceral adipose tissue reduction, improved lipid profiles, and cognitive benefits, making it a key study compound for metabolic dysfunction.

Thymalfasin · Tα1

Thymosin Alpha-1 is a naturally occurring 28-amino-acid peptide derived from thymosin fraction 5 of the thymus gland. Approved in over 35 countries for hepatitis B, hepatitis C, and as an immune adjuvant in cancer therapy, it enhances T-cell maturation, dendritic cell function, and NK cell activity. Research continues to expand into sepsis, COVID-19, autoimmune conditions, and vaccine response enhancement.

C₁₂₉H₂₁₅N₃₃O₅₅ · 3108.29 Da

Mounjaro · Zepbound

Tirzepatide is the first dual GIP/GLP-1 receptor agonist, approved for type 2 diabetes (Mounjaro) and obesity (Zepbound). By co-activating both incretin receptors, it achieves superior glycemic control and weight reduction compared to GLP-1 monotherapy — SURMOUNT trials showed up to 22.5% body weight reduction. It represents a new class of metabolic peptide therapeutics with broad cardiovascular and metabolic benefits.