Syn-Ake
PreclinicalDipeptide Diaminobutyroyl Benzylamide Diacetate
Syn-Ake is a synthetic dipeptide that mimics the mechanism of waglerin-1, a peptide found in Temple Viper venom, by antagonizing muscular nicotinic acetylcholine receptors and reducing muscle contraction. Applied topically, it reduces the depth of expression lines by temporarily relaxing facial muscles. It has become a common high-end cosmetic ingredient positioned as a non-injectable alternative to botulinum toxin.