Overview
Syn-Ake is a synthetic dipeptide that mimics the mechanism of waglerin-1, a peptide found in Temple Viper venom, by antagonizing muscular nicotinic acetylcholine receptors and reducing muscle contraction. Applied topically, it reduces the depth of expression lines by temporarily relaxing facial muscles. It has become a common high-end cosmetic ingredient positioned as a non-injectable alternative to botulinum toxin.
Routes of Administration
Cosmetic serum/cream formulations
Research Profile
Mechanism of Action
Pharmacokinetics
Key Research Findings
Side Effects & Safety
Research Search Terms
Links open PubMed searches for peer-reviewed studies on this peptide.
Frequently Asked Questions
Syn-Ake is a synthetic dipeptide that mimics the mechanism of waglerin-1, a peptide found in Temple Viper venom, by antagonizing muscular nicotinic acetylcholine receptors and reducing muscle contraction. Applied topically, it reduces the depth of expression lines by temporarily relaxing facial muscles. It has become a common high-end cosmetic ingredient positioned as a non-injectable alternative to botulinum toxin.
The reported half-life of Syn-Ake is Topical; no significant systemic absorption at cosmetic concentrations. Half-life refers to the time required for the plasma concentration to decrease by half through metabolic clearance.
In research settings, Syn-Ake is typically administered via: topical. Route selection affects onset, bioavailability, and duration of action.
Syn-Ake is currently at the Preclinical research — studied in cell cultures and animal models, with no approved human clinical trials. stage.
Syn-Ake profiles on Peptide United are for research and educational purposes only. This compound is not approved for human therapeutic use unless specifically noted. Always consult a qualified healthcare professional.
Related Compounds