Overview
Palmitoyl Tripeptide-1 is a lipopeptide created by palmitoylating GHK (glycyl-histidyl-lysine), the same sequence as GHK-Cu without copper. The palmitoyl group enhances skin penetration, while the GHK sequence signals fibroblasts to upregulate collagen, elastin, and hyaluronic acid synthesis. It is a primary active ingredient in Matrixyl formulations and widely used in anti-aging cosmetics with clinical data supporting wrinkle reduction.
Routes of Administration
Topical
Anti-aging cosmetic creams and serums
Research Profile
Mechanism of Action
Pharmacokinetics
Key Research Findings
Side Effects & Safety
Research Search Terms
Links open PubMed searches for peer-reviewed studies on this peptide.
Related Compounds