Research comparison
Ipamorelin vs Sermorelin
Side-by-side comparison of research status, mechanisms, pharmacokinetics, and administration routes.
Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. Unlike other GHRPs, it stimulates GH release with high selectivity — producing minimal cortisol, ACTH, or prolactin elevation. It is among the most studied GHRPs for its clean GH pulse profile, making it a preferred research peptide for GH axis studies with reduced side effect concern.
Research Status
Preclinical Research
Half-Life
~2 hours
Molecular Formula
C₃₈H₄₉N₉O₅
Molecular Weight
711.86 Da
CAS Number
170851-70-4
Research Categories
Growth Hormone Axis
Routes of Administration
Sermorelin is a synthetic analog of the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH). It stimulates the pituitary to produce and secrete growth hormone in a pulsatile, physiologic manner. FDA-approved for GH deficiency in children, it is extensively researched in adults for body composition, sleep quality, and age-related GH decline.
Research Status
FDA Approved
Half-Life
10–20 minutes
Molecular Formula
C₁₄₉H₂₄₆N₄₄O₄₂S
Molecular Weight
3357.88 Da
CAS Number
86168-78-7
Research Categories
Growth Hormone Axis, Anti-Aging & Longevity
Routes of Administration
Full mechanism comparison
Mechanism of action, pharmacokinetics, and research findings comparison available on the Researcher plan.
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