Peptide United

Research comparison

Hexarelin vs Ipamorelin

Side-by-side comparison of research status, mechanisms, pharmacokinetics, and administration routes.

Hexarelin

Examorelin · EP 23905 · His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH₂

Phase II

Hexarelin is one of the most potent synthetic GHRP compounds, producing the largest GH pulse among GHRPs. Beyond its GH-stimulating properties, research highlights direct cardioprotective effects through CD36 receptor binding, independent of GH or IGF-1. Studies show benefits in heart failure models, myocardial infarction recovery, and protection against ventricular dysfunction.

Research Status

phase2

Half-Life

~2 hours

Molecular Formula

Molecular Weight

CAS Number

140703-51-1

Research Categories

Growth Hormone Axis, Cardiovascular

Routes of Administration

Subcutaneous (SQ)Intravenous (IV)
Ipamorelin

NNC 26-0161

Preclinical

Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. Unlike other GHRPs, it stimulates GH release with high selectivity — producing minimal cortisol, ACTH, or prolactin elevation. It is among the most studied GHRPs for its clean GH pulse profile, making it a preferred research peptide for GH axis studies with reduced side effect concern.

Research Status

Preclinical Research

Half-Life

~2 hours

Molecular Formula

C₃₈H₄₉N₉O₅

Molecular Weight

711.86 Da

CAS Number

170851-70-4

Research Categories

Growth Hormone Axis

Routes of Administration

Subcutaneous (SQ)

Full mechanism comparison

Mechanism of action, pharmacokinetics, and research findings comparison available on the Researcher plan.

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