Peptide Database

FPF 1070

Cerebrolysin is a mixture of neuropeptides and neurotrophic factors derived from porcine brain proteins. It mimics the actions of endogenous neurotrophic factors (NGF, BDNF, CNTF), promoting neuronal survival, synaptogenesis, and neuroplasticity. Approved in multiple countries for Alzheimer's disease, stroke recovery, and TBI, clinical trials show improvements in cognitive function, activities of daily living, and brain MRI outcomes.

Cortexin polypeptide complex

Cortexin is a polypeptide complex derived from the cerebral cortex of calves or pigs, containing a mixture of neuropeptides and neurotrophic factors. Approved in Russia for stroke, TBI, epilepsy, and cognitive disorders, it exhibits neuroprotective, nootropic, and anticonvulsant properties. Research supports improvements in cognitive function, reduced neurological deficit after stroke, and accelerated recovery from brain injury. It is conceptually similar to Cerebrolysin but derived from cortical tissue.

N-phenylacetyl-L-prolylglycine ethyl ester · GVS-111

Noopept is a dipeptide-derived nootropic approved in Russia for cognitive disorders and memory impairment. It is hydrolyzed in vivo to release cycloprolylglycine, an endogenous neuropeptide. Research demonstrates neuroprotective, memory-enhancing, and anxiolytic effects, upregulation of BDNF and NGF in the hippocampus and cortex, and potential benefits in Alzheimer's disease models. It is significantly more potent than piracetam on a weight-for-weight basis.

Pitocin · the "bonding hormone"

Oxytocin is a 9-amino-acid neuropeptide produced in the hypothalamus and released by the posterior pituitary. Beyond its classic roles in parturition and lactation, research demonstrates effects on social bonding, trust, empathy, fear extinction, and autism spectrum disorder. Intranasal oxytocin research has produced mixed results in clinical trials, but it remains one of the most studied peptides in social neuroscience.

ADH · Antidiuretic Hormone

Vasopressin (AVP) is a 9-amino-acid neuropeptide produced in the hypothalamus and released by the posterior pituitary. It regulates water reabsorption via V2 receptors in renal collecting ducts and vasoconstriction via V1a receptors in blood vessels. Clinically used for diabetes insipidus, septic shock vasodilation, GI hemorrhage, and cardiac arrest. Extensive research also examines its roles in social bonding, memory, and stress responses.