Peptide Database

Trappin-2 · SKALP

Elafin is an endogenous serine protease inhibitor (serpin-like) peptide produced by epithelial cells at mucosal surfaces. It inhibits neutrophil elastase and proteinase 3, protecting tissues from excessive inflammatory damage, while also exhibiting direct antimicrobial activity against bacteria and fungi. Research focuses on inflammatory bowel disease, cystic fibrosis, ARDS, and vaginal microbiome modulation, where recombinant elafin is in Phase 2 trials.

KP-10 · metastin 45-54

Kisspeptin-10 is the shortest biologically active fragment of the kisspeptin peptide family, which are potent endogenous activators of the hypothalamic GnRH pulse generator. Research demonstrates it stimulates LH and FSH release and has been studied for infertility, hypogonadotropic hypogonadism, and modulating sexual aversion in psychological studies. It represents a key upstream regulator of the reproductive axis.