Peptide Database

Delta Sleep Inducing Peptide · Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

DSIP (Delta Sleep Inducing Peptide) is a nonapeptide first isolated from rabbit cerebral venous blood during electrically induced sleep. Research shows it promotes slow-wave sleep, reduces pain sensitivity, normalizes circadian rhythms, lowers cortisol, and exhibits stress-protective effects. It also stimulates LH release and may influence GH pulsatility. Multiple mechanisms of action are proposed; its receptor has not been fully characterized.

Epitalon · Epithalamin

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on the endogenous pineal peptide epithalamin. It is one of the most extensively studied longevity peptides, with Russian research demonstrating telomerase activation, telomere elongation, melatonin normalization, and extended lifespan in animal models. Long-term human studies show reduced all-cause mortality rates and improved biomarkers of aging.