Peptide Database

FST-344 · Follistatin isoform 344

Follistatin-344 is an isoform of follistatin, an endogenous glycoprotein that binds and neutralizes myostatin (GDF-8) and activin, thereby releasing the natural inhibition on muscle growth. Without myostatin's inhibitory signal, satellite cells proliferate and muscle fiber hypertrophy is dramatically enhanced. Gene therapy studies in animals and in rare myostatin-null humans demonstrate extreme muscle mass increases, driving significant research interest.