Peptide Database

AM

Adrenomedullin is a 52-amino-acid vasoactive peptide originally isolated from human pheochromocytoma. It is a potent vasodilator acting through CGRP receptors, promotes natriuresis, reduces inflammation, protects vascular endothelial barrier function, and enhances wound healing. Circulating AM levels rise in heart failure, sepsis, and critical illness — making it both a biomarker and emerging therapeutic target.

Copper Peptide GHK · Glycyl-L-histidyl-L-lysine copper

GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. Research demonstrates it stimulates collagen, elastin, and glycosaminoglycan synthesis, promotes wound healing, reduces inflammation, and activates protective antioxidant genes. Plasma levels decline with age, making it a significant anti-aging research target.

C₁₄H₂₄CuN₆O₄ · 340.84 Da (free ligand)

Cathelicidin · hCAP18/LL-37

LL-37 is the only known human cathelicidin antimicrobial peptide, derived from the C-terminus of hCAP18 protein. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and viruses by disrupting microbial membranes. Beyond direct killing, LL-37 modulates inflammation, promotes wound healing, and may have anticancer properties. Research focuses on chronic wound care, infection, and skin disorders like rosacea.

Arg-Gly-Asp · Integrin-binding peptide

RGD (Arg-Gly-Asp) is a tripeptide sequence found in many extracellular matrix proteins (fibronectin, vitronectin, collagen) that serves as the primary recognition motif for integrin receptors. RGD-containing peptides and scaffolds are extensively used in biomaterials research to promote cell adhesion, migration, and proliferation for tissue engineering, wound healing, and regenerative medicine applications.

Thymosin Beta-4 Fragment · Tβ4 fragment

TB-500 is a synthetic version of the active region of Thymosin Beta-4, a naturally occurring peptide found in virtually all human cells. Research shows it promotes actin polymerization and cell migration, which accelerates wound healing, muscle repair, and vascular growth. It is particularly studied for its ability to reduce inflammation and promote cardiac tissue repair.

C₂₁₂H₃₅₀N₅₆O₇₈S · 4963.44 Da

Tβ4 · LKKTETQ

Thymosin Beta-4 is the full-length 43-amino-acid peptide and one of the most abundant intracellular proteins in mammalian cells. It sequesters G-actin, regulating actin polymerization and cell motility, which underpins its role in wound healing, cardiac repair, and immune cell migration. Clinical trials have examined it for dry eye disease, epidermolysis bullosa, and cardiac repair after myocardial infarction.