Peptide Database

Symlin · synthetic amylin

Pramlintide is a synthetic analog of amylin, a peptide co-secreted with insulin from pancreatic β-cells. Approved as adjunct therapy to insulin in type 1 and type 2 diabetes, it slows gastric emptying, suppresses postprandial glucagon, and promotes satiety. It is the only amylinomimetic approved for clinical use and is studied for its complementary role to insulin in postprandial glucose control.

Egrifta · TH9507

Tesamorelin is a stabilized synthetic GHRH analog FDA-approved for reduction of excess abdominal fat in HIV-infected adults with lipodystrophy. It stimulates pulsatile GH secretion while preserving natural feedback regulation. Research demonstrates significant visceral adipose tissue reduction, improved lipid profiles, and cognitive benefits, making it a key study compound for metabolic dysfunction.