Research comparison
Selank vs Semax
Side-by-side comparison of research status, mechanisms, pharmacokinetics, and administration routes.
Selank is a synthetic heptapeptide analog of tuftsin developed by the Russian Institute of Molecular Genetics. Approved in Russia for anxiety and cognitive disorders, it exhibits anxiolytic effects comparable to benzodiazepines without sedation or dependence. Research shows it modulates GABA, serotonin, and dopamine systems, enhances BDNF expression, and improves memory consolidation and learning.
Research Status
FDA Approved
Half-Life
~5–10 minutes in serum; nasal effects last 1–3 hours
Molecular Formula
C₃₃H₅₇N₁₁O₉
Molecular Weight
751.87 Da
CAS Number
129954-34-3
Research Categories
Cognitive Enhancement, Immune Support
Routes of Administration
Semax is a synthetic heptapeptide analog of ACTH(4-7) developed in Russia, where it is approved for stroke, TBI, peptic ulcers, and cognitive enhancement. It upregulates BDNF and its receptor TrkB, promotes dopamine and serotonin turnover, and has demonstrated neuroprotective effects in ischemia models. Research highlights improvements in attention, memory, and recovery from neurological injury.
Research Status
FDA Approved
Half-Life
~20 minutes (active metabolite activity is prolonged)
Molecular Formula
—
Molecular Weight
—
CAS Number
80714-61-0
Research Categories
Cognitive Enhancement, Neuroprotection
Routes of Administration
Full mechanism comparison
Mechanism of action, pharmacokinetics, and research findings comparison available on the Researcher plan.
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