Research comparison
Epithalon vs GHK-Cu
Side-by-side comparison of research status, mechanisms, pharmacokinetics, and administration routes.
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled on the endogenous pineal peptide epithalamin. It is one of the most extensively studied longevity peptides, with Russian research demonstrating telomerase activation, telomere elongation, melatonin normalization, and extended lifespan in animal models. Long-term human studies show reduced all-cause mortality rates and improved biomarkers of aging.
Research Status
Preclinical Research
Half-Life
Short; longer-term effects persist after cyclic dosing
Molecular Formula
—
Molecular Weight
—
CAS Number
307297-39-8
Research Categories
Anti-Aging & Longevity, Sleep & Circadian
Routes of Administration
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. Research demonstrates it stimulates collagen, elastin, and glycosaminoglycan synthesis, promotes wound healing, reduces inflammation, and activates protective antioxidant genes. Plasma levels decline with age, making it a significant anti-aging research target.
Research Status
Preclinical Research
Half-Life
Rapid — minutes in plasma; topical activity persists longer
Molecular Formula
C₁₄H₂₄CuN₆O₄
Molecular Weight
340.84 Da (free ligand)
CAS Number
89030-95-5
Research Categories
Healing & Recovery, Skin & Cosmetic, Anti-Aging & Longevity
Routes of Administration
Full mechanism comparison
Mechanism of action, pharmacokinetics, and research findings comparison available on the Researcher plan.
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